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Antimicrobial and Bioactivity Evaluation of Laser-Modified Biodegradable Magnesium Alloy Coated with Chitosan–Graphene Oxide

Authors :

Seyed Alireza Ensaniat¹ Ali Safary² Farid Naeimi³ Hamid Reza Bakhsheshi Rad⁴ Monireh Ganjali⁵

1- پژوهشگاه مواد و انرژی 2- دانشگاه آزاد اسلامی واحد نجف آباد 3- دانشگاه آزاد اسلامی واحد نجف آباد 4- دانشگاه آزاد اسلامی واحد نجف آباد 5- پژوهشگاه مواد و انرژی

Keywords :

Akermanite،Antimicrobial،Bioactivity،Chitosan،Coating،Graphene oxide،Laser texturing،Magnesium alloy

Abstract :

The similarity between the elastic modulus of pure magnesium and that of natural bone, along with the absence of a need for secondary surgery to remove the implant, has made magnesium alloys promising candidates for medical implants. However, these materials still face limitations in their mechanical properties and biological performance. Therefore, the development of polymeric coatings has been considered an effective strategy to overcome these drawbacks. Chitosan has been employed due to its favorable biocompatibility and mechanical characteristics, while graphene oxide has been incorporated as a bioactivity-enhancing agent owing to its antimicrobial properties. The coatings were fabricated using a dip-coating method, and the effects of different GO concentrations (0, 0.25, 1, and 2 wt%) on antimicrobial and bioactive properties were evaluated. The results demonstrated that the coated samples exhibited significantly improved antimicrobial activity and bioactivity.