0% Complete
English
صفحه اصلی
/
سی و دومین کنفرانس ملی و دهمین کنفرانس بین المللی مهندسی زیست پزشکی ایران
Application of Nanomaterials in Biomaterials for the Regeneration of Bone and Cartilage Tissues
نویسندگان :
Behnaz Alijani
1
Niloufar Kazami
2
1- دانشگاه آزاد نجف آباد
2- Polytechnic University of Madrid
کلمات کلیدی :
nanomaterials،bone tissue regeneration،cartilage tissue regeneration،nanocomposites،hydroxyapatite،poly (lactic-co-glycolic acid) (PLGA)،type I collagen،iron oxide nanoparticles (Fe₃O₄)
چکیده :
This study investigates the application of nanomaterials in biomaterials for the regeneration of bone and cartilage tissues. The aim of this research was to design and evaluate nanocomposite scaffolds composed of hydroxyapatite (nHA), poly (lactic-co-glycolic acid) (PLGA), type I collagen, and iron oxide nanoparticles (Fe₃O₄) for use in bone and cartilage tissue engineering. Electrospinning was employed for scaffold fabrication. Experimental results demonstrated that nHA/PLGA nanocomposite scaffolds exhibited excellent mechanical properties, including high compressive strength (20±1.5 MPa), along with superior biological performance such as high biocompatibility and osteoblast viability of 90±5%. Furthermore, collagen/polymer-based scaffolds, due to their outstanding biological characteristics—especially in cartilage tissue repair—promoted significant chondrocyte growth and differentiation into adipocyte-like cells. Additionally, iron oxide nanoparticles (Fe₃O₄) imparted magnetic properties to the scaffolds, enabling their use in specialized applications such as targeted drug delivery, scaffold degradation monitoring, and magnetic field-mediated tissue stimulation. Histopathological and microscopic analyses confirmed the successful regeneration of bone and cartilage tissues in animal models. This study highlights that nanomaterials can effectively enhance the performance of biomaterials for tissue engineering applications.
لیست مقالات
لیست مقالات بایگانی شده
Impact of Impeller Blade Number on the Hemodynamic Performance of Specially Designed Mini VAD
Nasser Alizadeh - Hanieh Niroomand-Oscuii - Farzan Ghalichi
Quantum Computing for AI: Current Status and Future Roadmap
Nayereh Majd
تاثیر مولفه های هوش معنوی بر قضاوت حرفه ای حسابرسان
علیرضا عظیمی ثانی
تاثیر هوش مصنوعی در مدیریت بحران زنجیره تامین
علیرضا فولاد - شایان مسگر - احمدرضا مسئله - حسین پورابراهیم گیل کلایه
Biomedical Applications of Pectin Nanomaterials: Progress and Perspectives
Maryam Rajabzadeh-khosroshahi - Ali Baradar Khoshfetrat - Mehdi Salami-Kalajahi
Fixed-Frequency Impedimetric Detection of Sickle Cells Using Interdigitated Electrodes
َArezoo Savlani - Mobina Ghanbari - Mohammadjavad Bouloorchi Tabalvandi - Majid Badieirostami
Impact of Dynamic and Static Sports on Growth and Anthropometric Characteristics (Height, Weight, BMI) in Children and Adolescents
Amin Partovi fard - Mahmoodreza Azghani - Sadra Jalali - Samin Asghari
Static and Dynamic WPLI on Stressful Scenarios: an EEG Study
Nasrin Dehghani - Negin Joghataei - Zahra Ghanbari - Mohammad Hassan Moradi
نقش مشوق های مالی به عنوان تعدلیگر در رابطه بین هنجارهای ذهنی و رفتارهای حافظ محیط زیست در بین دانشجویان تحصیلات تکمیلی دانشگاه آزاد تبریز
سجاد محبی - اکبر علیزاده - مجید پابرجای زنجانی
پیشبینی سود با استفاده از هوش مصنوعی
الهه هادی زاده
بیشتر
ثمین همایش، سامانه مدیریت کنفرانس ها و جشنواره ها - نگارش 42.5.2